Job Qualifications

  • Basic experience or eagerness to learn manufacturing processes (Tangential Flow Filtration and Chromatography).

  • Bachelor’s (+5) or Master’s (+3) degree in cell or molecular biology, biomedical or chemical engineering, biochemistry, or a related field.

  • Nucleic acids: synthesis and purification, working knowledge of mRNA biology (e.g. sequence, structure) .

  • Molecular biology: Polymerase chain reaction (PCR), qPCR, RT-PCR, molecular cloning (e.g. Gibson or Golden Gate), agarose gel electrophoresis, Fragment analyzer.

  • Polyacrylamide gel electrophoresis (PAGE), western blotting, other forms of immunoblotting (e.g. dot and slot blots), silver staining, AKTA or FPLC purification, Bioanalyzer are preferred.

  • Cell biology: cell line and primary cell culture maintenance, expansion, banking, transfection optimization

  • Automation experience will be a differentiator.

  • Deep understanding and practical knowledge of the scientific method and selection of experimental controls

  • High attention to detail including planning, executing, and documenting experiments.

  • Communication skills including protocol writing, working directly with internal/external clients, PowerPoint.

How to apply:

Please send an email (subject: Manufacturing Team Lead) to karla@moligotech.com with your CV and motivation letter attached.

Research and Production Engineer

Job Description

The Research and Production Engineer is a motivated self-starter who takes initiative, asks questions, seeks answers, and can make headway at the lab bench.

He/She will work on ssDNA manufacturing for clients, collaborators and for internal use, but will also contribute in implementing new methods to synthesize, purify, and scale up ssDNA production, together with Process Development team. He/She will be involved in the execution of both upstream/downstream unit operations and use of methods to quality control.

Key Responsibilities

  • Manufacture ssDNA for client projects and internal use. 

  • Document all work in an electronic lab notebook, manufacturing execution system, lab execution system, lab information system, quality management system, and process knowledge database as appropriate. 

  • Support the implementation of manufacturing processes (Tangential Flow Filtration and Chromatography ). 

  • Plan and execute client and scientific projects. Troubleshoot unit operation performance 

  • Report on internal and client project status and product critical quality attributes (CQAs).

  • Present/Involved on major developments and innovation initiatives.

  • Create and support the development of workflows, SOPs, and related, documentation for systems, R+D, tech transfer, and quality processes.  

  • Collaborate with Process Development and R&D teams transferring new process technologies and analytical techniques from development to manufacturing.

  • Maintain and draft/review Standard Operating Procedures (SOP) used in Manufacturing.

  • Execute and implement manufacturing strategies to ensure efficient and effective production ssDNA.